Actually, the main point I was trying to make was that it wouldn't make much difference either way. Most types of interference caused by multiple transmitters being used wind up hurting old, cheap, or unmaintained equipment. Good equpment has few problems of any kind, except when you get a signal right on your channel, such as when someone on your channel turns on their transmitter in the pits.

The layout you mention would only pose a bit of a problem if the two guys at the far end from you are using channels that would wind up causing interference on your channel, and your airplane was much closer to them than to you.