Just a quick look at the VC10 indicates a 67 inch WS x 72inch length does the trick at 1/26 scale. Guessing an average chord of 9", which results in about 600 sq. inch wing area.
I would guess 60 oz empty airframe plus 20% for heavier construction (more lite ply, bigger longerons, etc) - say 75 oz for the bare airframe, perhaps 120 oz. AUW.

If all about right, the VC10 would have a wing loading of 29 oz/sq.ft. Certainly not unheard of but she would require langing gear or a bungee launch. Leaning away from true scale, a larger average wing chord of 10 inches, ups the wing area and lowers the wing loading. Everything becomes more favorable - stall speed drops, landing speed decreases, etc.

With a decent thrust/weight of 0.5, the static thrust would be only 60 oz. The two MF480's on my TBJ develop 52 oz static. Four MF480's would give you almost .8 thrust/weight

I would say this is a viable project but AUW will be the issue and will require careful detail to construction. Yuor choice of air foil will make or break this.

Go for it, post lots of pix.