We have our backups on another drive, but we also have 3 computers backed up on that drive.
I ran CCleaner and defraged my drive a few days ago.
splcrazy, I used to run CA and that was a memory huge memory hog compared to AVG. I might try Avast just to try it, but I"m not sure.
I have an 80gb hard drive with 45gb of free space let. I doubt that's too much.