The real single biggest difference in float flying is:
It's harder to walk out and get your plane if the engine quits.

Everything else is really not much different, and there are no potholes or cowflops on the runway to avoid.

Just fly the plane. THe wheel does not need re-invention. Go fast, pull up, fly around, land, taxi in. Just like on wheels.

The second biggest thing is: Runway grit does not collect on the oily goo on your airplane.