Might be a nuisance switching back and forth. The 4-stroke will weigh much more and might have a different "footprint" of mounting holes. The bug in the pudding is that you may have to add 4 oz of weight to the 2-stroke set-up . . . reducing it's speed in climbs. Whatever you can do with the battery may help: forward with the 2 & moved aft with the 4.

Have fun.

You never did tell us the model. Scale? Sport? Aerobatic? Very aerobatic? Not all airframes are born equal. No matter which sneakers you put on a pig it will never run fast.

If you're like me you won't be using the two-stroke in the plane much. Use the right prop and the four will likely wring out the model well enough.