Need more info,

Sounds like you are not arming the Esc.
Remove the prop to be safe.
Plug in the esc with throttle stick Down.
You should hear a beep, now raise the
throttle stick to full Throttle. Should beep
again, now lower throttle stick. You should
hear a serie of beeps (3or4) depending on
your battery size. The Esc should be armed
now.?? Slowly raise the throttle stick, motor
should run.

Bob