Automotive Paint?
As far as my experience with Bondo filler and glazing compound, I have never found anything that did not give good coverage and adhesion over it. I use the putty very sparingly and only over fiberglass. Then I use the surface glazing putty ( red tube ) to fill imperfections in the Bondo surface. I also use the glazing putty applied directly to ABS plastic after lightly sanding and cleaning the surface. For wood, I use a good hobby putty and after I spray the first coat of primer, I then fill the imperfections with the glazing putty applied directly to the primer surface before sanding the primer. Repeat as many times as necessary and you'll end up with a flawless surface for your paint.
Good luck!