I prefer to set my trims for level flight at the cruising speed of the airplane. If I need to climb I add power, if I need to decend I reduce power. Set up this way, take-offs at full power need little to no input from the elevator for a nice climb-out from the runway. Landings are controlled by a combination of power and elevator. On really 'floaty' type of airplanes, I might add a couple of clicks of down trim on the elevator to aid in landing and dealing with ground effect.
I like to fly in a scale manor, and this 'system' has worked well for me. It really all comes down to what works for you and what helps you to fly better.
Cheers!! BH