Matt,
With the 100 octane fuel you could probably increase the compression slightly. I don't remember what the C/R of Todd's engine is - I'm sure he can tell you. Higher compression is generally good as long as you have the fuel to support it. It sounds like you do. A higher compression ratio generally increases efficiency. The only GOOD reason to run a lower compression ratio is to allow you to use lower cost (low-octane) fuel. Simply running high-octane fuel without making any other tuning adjustments (besides mixture) will NOT increase power output. To get more power while using high octane fuel (compared to running lower octane fuel) you would need to increase the compression ratio or increase the ignition timing (as you've already suggested).

A good ignition with an adjustable / programmable timing curve would be nice Ed.

John Pavlick
Team Black Magic