This work might make sense if you were racing in a class that everyone had to start with the same engine and these mods were allowed.
For me I'll just buy the right engine in the first place. Jett, BVM, Nelson and the like have this figured out pretty well.

If you are into making cheaper engines try to perform at high RPM's then it just makes sense to me to start with an engine that's built for revs.
If I wanted cheap speed type performance, I'd start with a DF engine. At least the rod will hold up to the revs.

Just like any other engine, there really is no replacement for displacement. Just buy a bigger cheap engine.

I was in the 2-stroke motorcycle racing business in the 80's and it's a real science getting the port timing better than the factory did.
The best mods in 2-strokes were light flywheels, reed valves, matching the C/R to the fuel, and the biggest was in the exhaust system.
A properly tuned pipe felt like it doubled the power.