My CMP ME-109's all weighed about 16 pounds so far. Those using a glow motor had weights about 14 pounds dry.
Its not much different then most warbirds for take off. Ease into the throttle and feed in right rudder. Depending on your CG, if you DONT change the landing gear location to be slightly more forward(which requires a lot of work), you may have to be careful you dont nose over on take off. So..keep elevator enough to prevent that. I had my CG on the 1st one at 108mm and the 2nd one at 110mm. The 2nd one is much easier to have a smooth take off rollout...but i did shim the gear forward. Im using the Sierra Giant scale gear designed for the stock gear placement with only a minor shim.

For landing, I would feed in half flaps on the downwind leg prior to baking around for final approach. once i was lined up with the runway, Id add in full flaps(if the wind wasnt blowing much). As long as you keep the nose more or less slightly down, the plane "floats" along quite well on the downslope glide plath. I dont wanna say floats too much because you dont wanna cut the power till your at least over the threshold and maybe a couple feet off the ground. She doesnt feel ehavy when landing, even at 16 pounds. I did NOT have the upper inner radiator flaps deployed and have never done so while the plane was in the air. Remember, I have separate servos for those. If running both the bottom and top radiator flaps via one servo....you will probably need to keep your speed up a little more then I do because the upper flaps deployed upwards will cause more drag and will also try to push the plane down some.

I wouldnt recommend landing the plane without flaps at all unless there was a decent 6+mph headwind.