Fuels and Health Issues
#1
Thread Starter

It may be a good Idea to read more of the Health issues of fuels. [edit] Health and safety
Methanol is toxic by two mechanisms. Firstly, methanol (whether it enters the body by ingestion, inhalation, or absorption through the skin) can be fatal due to its CNS depressant properties in the same manner as ethanol poisoning. Secondly, in a process of toxication, it is metabolised to formic acid (which is present as the formate ion) via formaldehyde in a process initiated by the enzyme alcohol dehydrogenase in the liver. The reaction to formate proceeds completely, with no detectable formaldehyde remaining.[2]. Formate is toxic because it inhibits mitochondrial cytochrome c oxidase, causing the symptoms of hypoxia at cellular level, and also causing metabolic acidosis among a variety of other metabolic disturbances[3]. One of the common symptoms seen in methanol poisoning is permanent blindness by destruction of the optic nerve.[4] Fetal tissue will not tolerate methanol. Dangerous doses will build up if a person is regularly exposed to vapors or handles liquid without skin protection. If methanol has been ingested, a doctor should be contacted immediately. The usual fatal dose is 100–125 mL (4 fl oz). Toxic effects take hours to start, and effective antidotes can often prevent permanent damage. This is treated using ethanol or fomepizole.[5] Either of these drugs acts to slow down the action of alcohol dehydrogenase on methanol by means of competitive inhibition, so that it is excreted by the kidneys rather than being transformed into toxic metabolites.
The initial symptoms of methanol intoxication are those of central nervous system depression: headache, dizziness, nausea, lack of coordination, confusion, drowsiness, and with sufficiently large doses, unconsciousness and death. The initial symptoms of methanol exposure are usually less severe than the symptoms resulting from the ingestion of a similar quantity of ethanol.
Once the initial symptoms have passed, a second set of symptoms arises 10–30 hours after the initial exposure to methanol: blurring or complete loss of vision, together with acidosis. These symptoms result from the accumulation of toxic levels of formate in the bloodstream, and may progress to death by respiratory failure. The ester derivatives
Methanol is toxic by two mechanisms. Firstly, methanol (whether it enters the body by ingestion, inhalation, or absorption through the skin) can be fatal due to its CNS depressant properties in the same manner as ethanol poisoning. Secondly, in a process of toxication, it is metabolised to formic acid (which is present as the formate ion) via formaldehyde in a process initiated by the enzyme alcohol dehydrogenase in the liver. The reaction to formate proceeds completely, with no detectable formaldehyde remaining.[2]. Formate is toxic because it inhibits mitochondrial cytochrome c oxidase, causing the symptoms of hypoxia at cellular level, and also causing metabolic acidosis among a variety of other metabolic disturbances[3]. One of the common symptoms seen in methanol poisoning is permanent blindness by destruction of the optic nerve.[4] Fetal tissue will not tolerate methanol. Dangerous doses will build up if a person is regularly exposed to vapors or handles liquid without skin protection. If methanol has been ingested, a doctor should be contacted immediately. The usual fatal dose is 100–125 mL (4 fl oz). Toxic effects take hours to start, and effective antidotes can often prevent permanent damage. This is treated using ethanol or fomepizole.[5] Either of these drugs acts to slow down the action of alcohol dehydrogenase on methanol by means of competitive inhibition, so that it is excreted by the kidneys rather than being transformed into toxic metabolites.
The initial symptoms of methanol intoxication are those of central nervous system depression: headache, dizziness, nausea, lack of coordination, confusion, drowsiness, and with sufficiently large doses, unconsciousness and death. The initial symptoms of methanol exposure are usually less severe than the symptoms resulting from the ingestion of a similar quantity of ethanol.
Once the initial symptoms have passed, a second set of symptoms arises 10–30 hours after the initial exposure to methanol: blurring or complete loss of vision, together with acidosis. These symptoms result from the accumulation of toxic levels of formate in the bloodstream, and may progress to death by respiratory failure. The ester derivatives
#3

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From: Las Vegas, NV, ANGUILLA
Water is toxic (deadly) in enough volumn...actually classified as water intoxication. A woman died in a radio station stunt to see who could drink the most water in an hour. Common table salt is very toxic at high concentration which is not a whole lot of salt. Just need to be sensible about this stuff. When I was a kid we used Testor 39 glow fuel which contained a ton of nitrobenzene (the shoe polish smell) which is an aggressive carcinagen. Us old timers are still kicking around even after all this stuff and a bunch of asbestos stuff in our chemistry sets.
#4
Senior Member
What it does say, is that you should not have frequent exposures, because it builds up in your system over time. The poison lingers a long time before you get rid of it.
So do not drink it, nor wash your hands in it. If you make that a habit, your eye sight may suffer in due time.
So do not drink it, nor wash your hands in it. If you make that a habit, your eye sight may suffer in due time.
#5
Thread Starter

ORIGINAL: nitro joe
Nicely composed technical writing. Have you worked in the medical field?
Nicely composed technical writing. Have you worked in the medical field?
#6
Thread Starter

ORIGINAL: pe reivers
What it does say, is that you should not have frequent exposures, because it builds up in your system over time. The poison lingers a long time before you get rid of it.
So do not drink it, nor wash your hands in it. If you make that a habit, your eye sight may suffer in due time.
What it does say, is that you should not have frequent exposures, because it builds up in your system over time. The poison lingers a long time before you get rid of it.
So do not drink it, nor wash your hands in it. If you make that a habit, your eye sight may suffer in due time.
#8
Thread Starter

ORIGINAL: RunningMan
This is the interesting part,
"This is treated using ethanol or fomepizole."
So have a couple of beers after flying and you will be OK. [:-]
Steve
This is the interesting part,
"This is treated using ethanol or fomepizole."
So have a couple of beers after flying and you will be OK. [:-]
Steve
Capt,n
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From: Chiburbia,
IL
ORIGINAL: captinjohn
Hellow Joe: I have not, but like to know what may be harmfull to eyes or health. All I did was type in the one word "Methanol" into the Google search...and started reading. Then copied the health part so I could post it for others to read. Lots of good data to know. Best Regards, Capt,n
ORIGINAL: nitro joe
Nicely composed technical writing. Have you worked in the medical field?
Nicely composed technical writing. Have you worked in the medical field?
The post read to me, as if you were the author.
It's always admirable to credit the source when doing a cut & paste.



