if it's a primer it should be ok to paint on read the can does it say anything about top coating over it i think you will be ok yes the spray cans do overspray a lot i painted a motorcycle tank and side covers for a friend with automotive paint in my garage and i was lucky i had a mask on cause there was a cloud of vapours for like an hour in the garage i'll never do it again i used a large spray gun and the clear i used was to even worse yes use a mask even with the airbrush just a dust mask is good for the airbrush they would be at your hardware store

Greg