ORIGINAL: Lnewqban

I would say that trimming is similar, except regarding the relative incidence angles of the upper and lower wings, which has been discussed in these forums before.

Some like more positive for the upper and some like same angles for both, which seems to have a pronounced effect in pitch stability and abruptness of wing's stalls.

The theory behind it is that the more advanced wing should be the first wing to stall, in order to help dropping the nose sooner.
Also, it has been discussed that both wing's upwash and downwash interfere with each other and the tail.

Another characteristic to consider is that the more compact configuration of bipes reduces the inertia in pitch, yaw and roll respect to a high wing/low wing trainer.