One of the big issues is being able to put right thrust into the engine box. Which means you will need enough room to move it to the left side of the cowl enough to add atleast 2 degrees of right thrust into the motor and also to get the prop hub centered in the cowl. The Evo 160 is 11.4 inches in diameter so it will be really tough. I think John Redman tried to fit one in a Carf P-47 cowl and it didn't fit that.
A Moki 250 in a CARF jug is tough enough and it's only 10.5 inches in diameter.