As with any IC engine, the more often you use it the better it runs. The more Nitro the more trouble if left sitting for a long period of time, unless the proper after use lube procedure is practice.
I prefer to use minimal % of Nitro in any of my models, and 4/1 strait fuel using only synth. oil serves me pretty well to date with one of my oldest model now in its 'christ 33rd. year'.
33 YO X-Cell60 on strait fuel.