After reading your message, are you left handed?
If no, I would recommend that you fly mode 1
If I am not mistaken aileron and rudder on right
This will allow you to coordinate turns and to adjust for yaw when ailerons are applied and roll with rudder.
Having throttle and elevator on one side will allow you to manage power with one stick. After seeing pilots fly Mode 1, I don't know why we as a nation ever adopted Mode 2????
When I think about it maybe the question should be: Does anyone see an advantage or disadvantage to flying Mode 4? - aileron and throttle on the left stick with rudder and elevator on the right stick.