My first kit build was also the 4*60, great kit and great plane when finished. I agree with the other guys. It's not impossible, but it sure is easier to have your engine and mount when building your fuselage. Drilling the firewall holes and sucking up the blind nuts is much easier done when you get to that point in the manual instead of later on and trying to fish things through small holes and drilling holes with the cheeks in the way (of course you can always but a longer bit).
If your interested here is a thread with a lot of pics of my build, might give you a hint or two. [link=http://www.rcuniverse.com/forum/m_361392/anchors_361392/mpage_1/key_/anchor/tm.htm#361392]Putt's 4*60 build[/link].
Good luck and let us know if you run into any more questions, looking forward to seeing the pics of the finished project