I would agree with Ed on this one. Unless you are building a scale model for contest where the deviation would down rate the score, use every available advantage to assure that you have single engine control.
If you can't have light wing loading, then off set thrust is the next best solution to safer single engine flight.
To those that think off set thrust looks funny, it is better than the appearence of the scattered pieces.
ORIGINAL: Ed_Moorman
8 degrees out on both engines if you want to fly on 1 engine and not worry about rudder.
You lose 1% of forward thrust, but get 14% side thrust. I have tried lesser amounts and still seen the need for rudder. 4 degrees is definitely not enough.
Obviously, the spacing of the engines, the length of the fuselage and the size of the vertical tail all play into this equation. Right now I have 4 twins, 1 with engines straight ahead, 1 with 4-5 degrees and 2 with 7-8 degrees. I can tell the need for rudder on the first 2 when an engine quits.