RE: Multi Engine FIrst Build?
If this is going to be your first kit, keep the quality of the instructions in mind. With your RTF trainer and the ARF glider, you probably got a fairly complete set of instructions that took you through the assembly process. Depending on the kit, you can get anything from a set of "step-by-step instructions" to a very bare-bones "contruction guide", which says "... build the fuselage, build the wing, and put 'em together" without a lot of details.
Your other problem is that there aren't a huge number of commercially available kits for twins: NE-Aero and Cedar Hobbies have some sport models; Hobby Hangar has the Uravich 53" OV-10 Bronco (good kit, but not one I'd recommend for a first kit build). Tower used to have a Great Planes Profile P38 Lightning (Complete instructions, but Lightning's aren't reco'd as first twins). Wing Manufacturing has a short kit for an A26 and a P82 Twin Mustang. Your Twin Otter is an attractive airplane; if the supplier's instructions live up to their billing in the ad it might be a good choice. And if the time/money equation plays any part in the decision, the $120 TwinStar ARF merits consideration: it's not a kit, but you'd probably end up getting it in the air sooner.