RE: Adjusting CG on full or half-full tank?
Set up your plane with the tank empty. If when you fly the plane needs a significant amount of down to maintain level flight while inverted, then move the cg back in small increments. I like mine to need no more then 1 or 2 clicksworth of trim for hands off inverted flight, but I trim it for upright level flight. Any further back & Extras, Edges, Yaks & the like become a handfull.