You will need a game port, the kind that comes with sound cards for full-sized computers
I have seen a converter box that will let you use your laptop, but I have no information on it now. Try looking through this forum for mention of it. Also, some sims can use an LPT (printer, parallel) port.
Do you have a transmitter now? If so,
RealFlight has a version that comes with a cable to attatch your transmitter through the LPT port. Check it out at the
interface page.