Unless you plan to fly off water there is no need to use Titebond II. Regular original titebond is easier to use and allows as strong a joint to be made. I assemble with CA to hold things in place or use "T" pins into ceiling tile or Homasote which is laid over my actual building board and then use a syringe with a large bore needle (sand or file the point off for safety) to add a small bead around joints. This adds very little weight as you can put the glue just where you want it. Once the liquid evaporates the film "fillet" adds a tremendous amount of strength and in not affected by shock loads like CA is. I have seen more than one plane lost to CA failure. There are considerable health risks with CA and virtually none with Titebond. I have glued firewalls into giant scale planes with Titebond and the joint is just as strong as epoxy and maybe even stronger if the joint is a good fit. If it's not then no glue will really add strength. Adding mechanical joints such as box joints (yes I do have a pet peeve of referring to these joints as dovetails when they actually aren't) will add tremendous strength. Pinning with small dowels or skewers (bamboo) is another way to add strength without adding weight. A pinned box joint would be ideal and is used in some model construction.

There is one place however that CA is really a good answer to construction. In open framework where end grain is added to side grain here is the procedure. Add a few drops of thin CA to the end grain of the piece(s) being joined. This will fill the pores of the wood as it acts as a capillary action and pulls the glue into the pores of the wood. If you just add the glue to the parts and assemble without this the joint will be "starved" which means the glue will be pulled away from the joint and strength lost. Finally add medium CA to make the joint. Nothing sticks to CA like CA. I still add the Titebond fillet to this type of joint afterward and have never had one fail. I have had some fail that were only CA.

Clamping of Titebond joints doesn't need to be for very long. It will gain 70% of it's strength in about 15 minutes. If you have stress on the joint then more time may be needed.

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