I fly a MF480 with the 16/15/2 motor and a CC35 ESC. On 3s, the motor draws 32 amps, on 5s I'm guessing an amp draw of 50-ish.

This might be a bit much for the motor. The ESC should be OK as long as you limit full throttle and provide plenty of cooling air.

The 15C pack is OK for 32 amps or so. At full throttle, you will experience a large voltage sag so your power system may be self limiting in the current/voltage department.

Push the battery and it won't last long. Check the balance frequently.