A good place to start is deciding what you want to do with this model...is it just to build a "nice airplane" semi scale? or full scale?
if you ask 10 different people how to start building you will get 10 different answers. I would strongly suggest you consider your time frame for getting this model done, scratch building inevitably takes longer but is more gratifying..I know quite a few people who have half-finished dinosaurs in their shops in which they have invested hundreds of hrs. and $$$ only to give them away a few yrs. later because they "ran out of gas". The P6E is a fabulous aircraft that will provide many happy days of building.

If your shop is not set up make sure you have a sturdy, straight, and level building board....take your time and make sure everything is glued square up to center fuse line. I always start with tail section to get my feet wet and make some progress...but starting with the fuse also makes good sense..build it straight and true so you know you have a quality airframe that will provide many years of service and eliminate trouble shooting should you encounter any unusual flight characteristics. Make sure your wings have no twists in them...again straight and level..triple check before gluing...and as always keep it as light as possible....I use lots of small gussets to give added strength where needed.

I'm sure there are some "how too" books on scratch building out there somewhere. Good luck in your project..you will get good advice on this forum as you move through the procedures....but most of the fun will be in solving your own problems....take pride and do quality work.

We look forward to seeing your project take off !!