amax

Well I gotta say things have come A Long way since the last time I picked up a rattle can to paint. If you prefer the rattle can method, Instead of the Pro method, the Urethane Clear would be the better material to use, just make sure you use the Base Coat colors from the same manufacturer. The rattle can is a little less intimidating than the Spray Gun and Mixing your own chemicals is, But as Yota stated if it Ain't Spraying Right, you have no control or adjustment, or the ability to clean the tip out if it gets a heavy clog.
Spray methods will be close to the same with either method, Long Smooth Even Strokes with a 20% to 30% overlap. Prep for a rattle can paint job can sometimes take more work due to the Thinner Materials Sprayed from the can, rattle can primers are generally much thinner than those made for a Spray Gun, so they won't cover as deep a sanding scratches.
Both need a Good Clean Contained area to spray a Good Quality Paint Job, and an extremely clean surface to bond to. Both need Filtered Ventilation.
When you get over the Intimidation factor of the Spray Gun and mixing Paint Products IMO it's actually the easier way to get a Nice Paint Job, due to better Spraying Equipment with the Adjustability to Your spray style.